A double knockout against malaria

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منابع مشابه

Potent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

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Potent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

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Intermittent preventive treatment against malaria in infants in Gabon--a randomized, double-blind, placebo-controlled trial.

BACKGROUND Intermittent preventive treatment aims to maximize the protective effects of malaria chemoprophylaxis while minimizing the deleterious effects. METHODS In Gabon, 1189 infants received either sulfadoxine-pyrimethamine (SP; 250 and 12.5 mg, respectively) or placebo at 3, 9, and 15 months of age. Children were actively followed-up until 18 months of age. RESULTS In the intention-to-...

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Vaccines against malaria.

Despite global efforts to control malaria, the illness remains a significant public health threat. Currently, there is no licensed vaccine against malaria, but an efficacious vaccine would represent an important public health tool for successful malaria elimination. Malaria vaccine development continues to be hindered by a poor understanding of antimalarial immunity, a lack of an immune correla...

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Pooling success against malaria

Neotrópica and the nearby town of Golfito, involves building a medical clinic in La Gamba. The Rainforest of the Austrians has once again been collecting donations, this time to pay for the hospital's equipment. Thus the Rainforest of the Austrians is managing to involve and benefit the local community while continuing to work towards its primary goals of conservation, research and education. T...

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ژورنال

عنوان ژورنال: Science-Business eXchange

سال: 2009

ISSN: 1945-3477

DOI: 10.1038/scibx.2009.1164